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Even though some individuals with excess adiposity might be relatively metabolically healthy compared to others with a similar BMI, they may still be considered at risk for obesity-related primarily non-metabolic complications (e.g., osteoarthritis, gallstones, gastro-oesophageal reflux disease) 3

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IGF-1 does not rise with oral or sublingual sermorelin: IGF-1 is the measurable marker of growth hormone activity